Natural Remedies for a Urinary Infection in Pregnancy

UTI Be Gone

UTI Be Gone is a new program that provides people with natural remedies, techniques, tips, and detailed instructions on how to beat their urinary tract infection quickly. In the program, people will discover a lot of healthy foods that support them in the urinary tract infection treatment process. In addition, the program is designed by Sherry Han, who suffered from urinary tract infection for many years. Using antibiotics is not a good way to treat urinary tract infections since bacteria will boost resistance against antibiotics after each use. The only way to treat urinary tract infections permanently is to do that the natural and effective way. With UTI Be Gone, sufferers will know how to alleviate their problems once and for all. Sherry Han will show people how she got rid of this disease within a few weeks. Since Sherry Han released the program, she has received many positive comments from customers regarding their success.

Uti be gone Natural Urinary Tract Infection Cure Summary

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Universal precautions In 1985 the centers for

Urinary tract infection (UTI) Infections of the urinary tract are usually caused by bacteria, such as Escherichia coli, which travel from the colon to the urethra and bladder (and occasionally to the kidneys). Low resistance, poor diet, stress, and damage to the urethra from childbirth, surgery, catheteriza-tion, and so on can predispose individuals to infection. often a sudden increase in sexual activity triggers symptoms. UTIs recur frequently in males and females. Pregnant women are especially susceptible (pressure of the growing fetus keeps some urine in the bladder and uterus, allowing bacteria to grow), as are postmenopausal women (because of hormonal changes). older men are susceptible due to benign enlarged prostates. This can cause obstruction of the urethra and lead to infection. The incidence and severity of UTIs in HIV-positive people is somewhat greater than in the general population. HIV-positive women get more frequent infections at a younger age than their...

Clinical Uses Urinary Tract Infections

The fluoroquinolones are highly effective in uncomplicated urinary tract infection and are drugs of choice where bacterial resistance compromises routine P-lactam therapy (Chapter 6). Fluoroquinolone efficacy is augmented by their ability to eliminate carriage of uropathogenic E. coli in the intestine 45 . Excellent results follow standard short-course and single-dose regimens 46,47 .

KGF in Bladder Injury

Hemorrhagic cystitis is a complication often associated with chemotherapy using cyclo-phosphamide (CP) or its derivatives, but less frequently with radiotherapy. Remarkably, KGF was shown to almost completely ameliorate CP-induced ulcerative hemorrhagic cystitis in a rat model. This effect was achieved with a single iv injection of KGF 24 h before CP administration and maintained until at least 48 h later (94). Consistent with this observation, KGF has been shown previously in rats and rhesus monkeys to promote rapid proliferation of urothelial transitional epithelial cells (95). These studies support the clinical testing of Palifermin (rHuKGF) for the treatment of CP-induced bladder cystitis.

Young Woman with Recurrent Abdominal Pain

Just 3 days prior to the patient's current presentation, her gynecologist had prescribed trimethoprim and sulfamethoxazole for a presumed urinary tract infection. When the patient arrived in pain this time, she was complaining of much more severe abdominal pain, nausea with vomiting, bilateral leg pain with paresthesias, and generalized weakness such that she could not stand. She was a well-nourished but dehydrated young woman in obvious pain and very weak with a pulse of 125 bpm and a blood pressure of 142 105 mm Hg. Although she complained of abdominal pain, there was no localized tenderness or rebound pain. Her abdomen was distended and revealed scars from her appendectomy and laparoscopy. Neurological examination showed decreased motor strength in both legs and absent reflexes. Responses to pinprick, light touch, and proprioception were decreased. The physician surmised that the recent sulfamethoxazole therapy for the patient's urinary tract infection had induced this rather...

Clinical Application Of Btx In The Treatment Of Lut Dysfunction

In 1988, Dykstra and colleagues utilized external urethral sphincter injection of BTX in 11 patients with DSD resultant from spinal cord injury (17). Evidence of sphincter chemod-enervation was seen using electromyography (EMG), which corresponded to subjective and objective improvement in most patients. Objective improvement was seen in parameters including PVR, urethal pressure profile, and incidence of autonomic dysreflexia. Toxin effects lasted an average of 50 days. Sensory Disorders Interstitial Cystitis Pelvic Pain Disorders that BTX also has an inhibitory effect on the afferent innervation of the bladder. Concurrently, a significant amount of basic science research has suggested a large role of sensory neurons in the pathophysiology of the subset of OAB thought to suffer from sensory neuron dysfunction (SU and urgency-frequency syndrome) (discussed previously refs. 40 and 41). Further, research supports that neuronal actions may act as possible mediators of interstitial...

Requirements for Prokaryotic Growth

The range of organic carbon compounds uti-lizable by heterotrophs is vast virtually any compound synthesized by biological processes, as well as many xenobiotica (compounds synthesized in the laboratory which do not originate in nature), can be degraded by microbes. Different species of heterotrophic prokaryotes utilize considerably different numbers and kinds of carbon substrates. Some, such as the pseudomonads, are versatile and are known to utilize over 100 different carbon compounds as the sole source of carbon and energy. Their substrates include carbohydrates, sugar acids, polyols, fatty acids, primary alcohols, amino acids, and aromatic substances. In contrast to these versatile bacteria, several groups exist that are limited in their ability to decompose organic compounds. In this cat-

Man with Fever and Acute Polyarthritis

The patient gave a history of occasional sore throats that were rarely treated with antibiotics and a history of intermittent knee pain for several years. He complained of dysuria of one-week duration. He had no regular sexual partner and reported a new sexual contact one month previously. Social history revealed a seventh-grade education and employment as a parking lot attendant. His father died of cirrhosis and his mother, of suicide. He did not smoke but drank approximately 10 beers per week.

Vaginal candidiasis See candidiasis

Color change from what is normal for an individual occurs, a doctor should perform an examination to determine the cause. Any abnormal aromas of the vaginal area also need to be investigated by a doctor. Abnormal discharge can be due to infection and is frequently associated with pain, burning, itching, and painful urination. pelvic inflammatory disease (PID), herpes genitalis, other STDs, infection of the inside of the uterus, and inflammation of the vagina due to lack of estrogen are other possible causes of vaginal discharge.

The Doctorpatient Relationship

If a patient with voiding dysfunction is referred to the urologist for evaluation, he or she could be started on a medicine, sent for urodynamic studies, or treated for a urinary tract infection. Regardless, the patient needs to come back to talk about the improvement or worsening of symptoms and then another move will be made. Possibly an older man could end up going to the operating room for a transurethral resection of his prostate, or to the clinic for transurethral microwave therapy of his prostate, but many of these patients do very well on medical therapy and continue to have checkups for years and years. Likewise, women with incontinence may either see the urogynecologist or the urologist and have an ongoing relationship, assessing the wetness for years.

Detection of antiphospholipid antibodies aPL in dermatology

Prevention of recurrence of skin lesions depends not only on their severity, but also on the other features of the disease. There are no data concerning the frequency of recurrence of skin vessel thrombosis. In the literature, only one patient had two separate episodes of widespread cutaneous necrosis each was precipitated by surgical manipulation of the urinary tract in the presence of urinary tract infection (Del Castillo et al., 1997). As widespread cutaneous necrosis and or digital gangrene Del Castillo, L.E., Soria, C., Schoendorff, C., et al. 1997. Widespread cutaneous necrosis and antiphospholipid antibodies two episodes related to surgical manipulation and urinary tract infection. J. Am. Acad. Dermatol. 36, 872. Galli, M., Barbui, T. 2005. Antiphospholipid syndrome clinical and diagnostic utility of laboratory tests. Semin. Thromb. Hemost. 31, 17.

Diagnosis And Evaluation Of Lut Dysfunction

Botulinum Toxin Injection Anal Sphincter

Potential targets of botulinum toxin injection classified by urological disorder. DO, detrusor overactivity IC, interstitial cystitis SU, sensory urgency BPH, benign prostatic hypertrophy DSD, detrusor-sphincter dyssynergia. Fig. 1. Potential targets of botulinum toxin injection classified by urological disorder. DO, detrusor overactivity IC, interstitial cystitis SU, sensory urgency BPH, benign prostatic hypertrophy DSD, detrusor-sphincter dyssynergia. Routine urological assessment should include urinalysis and urine culture. Both of these studies are mandatory because urinary tract infection is a common cause of frequency, urgency, or incontinence. Serum creatinine should be used to evaluate renal function. Assessment of micturition is essential in the diagnostic work-up. Accordingly, uroflow offers a noninvasive method by which the urine flow rate is measured and can help to identify patients with outlet obstruction and or detrusor hypocontractility. Further, measurement of...

Penicillinaseresistant Penicillins

Blood levels - 2 limes greater lhan cloxacillin Acute hemorrhagic cystitis reported Acute abdominal pain wilh Gl bleeding wiinoul antibiotic-associated colitis also reported ANT1PSEUOOMONAL PENICILLINS NOTE Platelet dysfunction may occur wilh any ol the andpseudornonal pemolbns esp in renal failure patients Piperacillin tPiprociii 3-4 gm IV q4-6h (200-300 mg per kg psr day up lo 500 mg per kg per day). For urinary tract Infection 2 II 85 mEq Na pei gm

Ampicillin Amcill Omnipen Polycillin Principen

A penicillin-type semisynthetic antibiotic used to treat conditions caused by a broad spectrum of gram-negative and gram-positive organisms in the urinary, respiratory, and intestinal tracts. some of these conditions include cystitis, bronchitis, gonorrhea, and ear and eye infections. It is inactivated by penicillinase and therefore cannot be used against bacteria that produce this enzyme.

A 10Year Old Boy with Pain Induced Seizures

Over the next few years, the patient's calcium remained between 11.0 and 12.2 mg dL. His plasma PTH was stable, and he remained asymptomatic. Five years after the initial diagnosis, the patient developed dysuria and symptoms consistent with nephrolithiasis, and he thus underwent parathyroidectomy. Immediately before removal of any glands, the plasma PTH was 260pg mL. Three and one-half enlarged-appearing glands were then removed. Intraoperative PTH values of 50 pg mL and 56 pg mL were obtained at 25 and 45 minutes after gland removal. The observed decline in PTH indicated that the bulk of the hyperfunctioning tissue had been removed, and the surgery was completed. Histologic evaluation of the resected parathyroid tissue indicated diffuse hyperplasia of all four glands.

An Overview Of Urology

Urologists are masters of everything that has to do with the passage of urine, from its production in the kidney to its release through the urethra. They surgically correct problems such as obstructing posterior urethral valves in newborn boys or bladder outlet obstruction caused by benign prostatic hypertrophy in elderly men. Urinary tract infections, which affect every age group and can be quite destructive, make up a large proportion of cases seen by urologists, especially if it progresses to a worrisome infection of the kidney itself (pyelonephritis). These UTIs could actually represent serious underlying problems of the urinary system. Urologists, therefore, make use of sophisticated testing (laboratory urine analysis,

Diseases That Cause Vulvar Pain Vulvar Vestibulitis

Vulvar Vestibule Healthy

Women with VVS experience substantial pain with tampon insertion, insertion of a speculum, or with sexual activity. When the insertional pain is associated with sexual activity, women usually experience relationship difficulties with their partners. When this occurs, lowered self-esteem is common and some women can experience substantial depression (1,24,25). In the more severe cases, women can experience pain and burning on a day-to-day basis when walking, sitting, wearing clothing that comes in contact with the vulva, after exercise, and wiping after urination. If the inflammatory process includes the periurethral ducts of the vestibule, women may complain of urgency and frequency in the absence of a urinary tract infection. Symptoms can also be totally unpredictable and unprovoked.

Biofilms in medical systems

Urinary tract infections are most commonly caused by E. coli, Proteus mirabilis, Enterococcus, and Streptococcus spp., found in the gastrointestinal tract, and by pathogens directly transmitted through sexual activity. These infections include acute and chronic cystitis, struvite urolithiasis, chronic prostatitis, and catheter-associated infections. Once the microorganisms are established, they adopt the biofilm mode of growth. The bladder resists infection by the periodic passing of urine, which washes out unattached pathogens, and by sloughing of colonized uroepithelial cells on the glycosaminoglycan (GAG) mucous layer. The GAG layer is a very thin cover on the cell epithelium of the bladder that physically shields the bladder from surface pathogens. Catheter-associated infections increase by approximately 10 each day the catheter is in place. The organisms initially colonize the external surfaces, form a biofilm, and ascend into the bladder where the biofilm can act as a source of...

Diabetic Womans Episode

A 55-year-old woman with a 4-year history of type 2 diabetes mellitus was brought to the hospital emergency department (ED) by ambulance at 1 30 pm after she was found unconscious at home. At the scene her blood glucose concentration (measured on capillary blood with a portable glucose meter) was 17 mg dL (0.9 mmol L). She was given 50 mL of 50 dextrose (D50) intravenously in the ambulance before arrival at the ED and immediately awoke. In the ED she stated that she took her regular morning insulin dose at 11 30 am, but missed her usual lunch and ate only a peach. She began to feel weak in the shower, called her brother, and told him she was having another episode, and then passed out he immediately called emergency medical services. It was estimated she had been unconscious for 45 minutes. She denied recent fever, chills, nausea, vomiting, cough, chest pain, shortness of breath, or dysuria. She admitted to prior episodes of hypoglycemia, but never with loss of consciousness. Her past...

Diagnosis How Physicians Reason

A diagnosis dictates decisions and action. It can be a simple one, easy and quick to make the common cold, sprained ankle, pneumonia, cystitis (bladder infection). Or it can be more complex, requiring substantial thought and time bacterial endocarditis, a complex illness caused by a heart valve infection ulcerative colitis, sometimes beginning as mild diarrhea instead of the more dramatic bloody bowel movements dissecting aortic aneurysm, a tearing of the main artery leading from the heart and often mimicking the symptoms of a heart attack. A diagnosis, even a tentative one the answer to the questions What is wrong or What is going on allows the physician to make decisions and take action.

Structural and historical background

Quinolone antibacterial research and development has enjoyed an enormous worldwide effort since the early 1960s. During this time, more than 10,000 structurally related agents have been described in many hundreds of patents and journal articles. The product of this wealth of research has been a continually improving progression of marketed quinolone antibacterial agents. From the early days of Gram-negative-selective agents limited to treatment of urinary tract infection, the field has matured to provide broad-spectrum drugs capable of treating not only urinary tract infections but also systemic infections caused by Gram-positive and Gram-negative pathogens at sites ranging from skin to joints to the respiratory tract. Some newer agents incorporate activity against anaerobic pathogens, making them useful in surgical and gynecological infections. The pharmacokinetic performance of these agents has also been optimized, allowing for once-daily dosing of a subset of the newer...

Urology Outside The Operating Room

Patient 3 A 44-year-old woman, complaining of pelvic pain and urinary frequency, says she has been treated for presumptive urinary tract symptoms by her primary care physician but there has been no relief. She is otherwise healthy but exasperated by this ongoing pain. You send a urine sample to the lab for urinalysis and culture and to pathology to check for malignancy. You determine that after urinating, she has a post-void residual of 25 mL, so you schedule her for an in-office flexible cystoscopy, suspecting interstitial cystitis but wanting to rule out any abnormalities.

Differential Diagnosis

Glucose-6-phosphate dehydrogenase (G6PD) deficiency should also be considered in the differential diagnosis. The gene for G6PD is carried on the X chromosome, and consequently G6PD deficiency is a sex-linked disorder. Its incidence in African-American males is roughly 1 in 8. Erythrocytes of these individuals contain levels of G6PD that, although low, usually maintain an adequate reserve of reduced glutathione to prevent oxidation of hemoglobin. However, exposure to oxidizing substances (e.g., primaquine for prophylaxis of malaria, nitrofurantoin for urinary tract infection, or fava beans) or an acute febrile illness may overwhelm the fragile system operating with marginal levels of G6PD and lead to phagocytosis of red cells containing denatured hemoglobin (Heinz bodies). In interim periods, the erythrocytes of patients deficient in G6PD survive normally. G6PD deficiency is detected with a screening procedure followed by quantitative assay for specific enzymatic activity. The G6PD...

Cholesterol 101

Note too that if a patient's most recent sexual contact occurred more than 60 days before the onset of symptoms, her most recent sexual partner should be treated. Intercourse should be avoided until treatment is completed and symptoms have been resolved. It is generally recommended that the initial medical evaluation of HIV-positive women include screening for chlamy-dia as well as for vaginitis, urinary tract infection, syphilis, and gonorrhea along with a complete menstrual, sexual, obstetrical, and gynecological history and breast and pelvic exams. Some evidence suggests that sexually transmitted infections, including gonorrhea and chlamydia, are more common in HIV-positive women, but it is not clear yet whether this is a result of HIV infection or of high-risk behavior that is also responsible for acquisition of HIV infection itself.

Cytochrome P450 129

Cystitis An infection of the urinary bladder, usually occurring secondary to ascending urinary tract infections. Associated organs (kidney, prostate, urethra) may be involved. May be acute (with frequent and painful urination) or chronic (secondary to another lesion) possibly with pyuria as the only symptom. Antibiotics are useful in treating the

Echocardiography 165

Echinacea The leaves and root of the herb Echinacea (E. angustifolia or E. prupurea) have been used by Native Americans for a broad range of pains and illnesses. Echinaecein is the substance that knits skin and prevents germs from penetrating tissues. possibly the most important aspect of Echinacea is its immunostimulant capability for infectious diseases and other conditions like tonsilitis, bladder infections, colds, flu, and boils. The roots of this herb are used as a tonic and blood purifier, as well as for a variety of other conditions, and other pains and wounds. Advocates of the therapeutic value of Echi-nacea have cited test tube and animal studies to support these claims. Injections of purified Echinacea are believed to be relatively nontoxic even at high doses, although there have been reports of skin rashes and insomnia. Few clinical trials have been performed using either injected polysaccharides or oral over-the-counter Echinacea supplements, the most common form of this...

Gynecology

HIV-positive women who are essentially asymptomatic, with CD4 counts greater than 400, who are not sexually active and who have no new gynecological complaints can be followed with gynecological screening and pap smears annually. Symptomatic women, women with AIDS, and sexually active women should be scheduled for gynecological evaluations, Pap smears, and STD screening every six months. Interval assessment should occur whenever a woman presents with low abdominal pain vaginal or rectal discharge abdominal bloating genital sores new onset of swollen or painful inguinal nodes dysuria, hesi

Menopause 309

Estrogen replacement therapy is generally offered to menopausal women to reduce bothersome or debilitating symptoms (hot flashes, insomnia, decreased sexual functioning, decreased appetite, night sweats, weight loss, fatigue, vagini-tis, dysuria, etc.), to prevent demineralization of bones (leading to osteoporosis), and to offset changes in lipid metabolism related to heart disease. Estrogen is supplemented with progestin to offset the documented increase in endometrial cancer and potential increased risk of breast cancer

Immunosuppressants

Pulse IV CYC should be combined with CS for patients with poor prognostic factor(s), i.e. FFS X1. Pulse therapy acts more rapidly and engenders fewer side effects (hemorrhagic cystitis, leukopenia) than oral administration. Briefly, each CYC pulse (0.5-0.7 g m2) is administered every 15 days for the first 3 boluses, then every 3 weeks (WG and MPA) or monthly (PAN and CSS). When preferred (WG) or required (e.g., after failure of pulse CYC), oral CYC (2 mg kg d) should be prescribed. CYC should be sustained at least until remission is achieved, between 3 for pulse CYC and 18 months for oral CYC, then maintained for a total of 12 months for severe systemic PAN or CSS, whereas, for WG and MPA, it can be switched for maintenance therapy with met-hotrexate, azathioprine or mycophenolate mofetil, for an additional 1 or 2 years.

Outlook

In the past, most children with the most severe cases of spina bifida (myelomeningocele) died soon after birth, but today immediate surgery saves the lives of most of these children. They usually must have a series of operations as they grow and usually need special devices to help them walk. With this treatment, about 80 percent of these children can walk by the time they enter school. Most need special training (such as how to insert catheters) to manage bowels and bladder and prevent serious bladder infections and kidney problems. Special diets and schedules allow many children to achieve

Want To Go Home

The patient is a 56-year-old white male who presented to the emergency department with a history of benign prostatic hypertrophy and now had fever, chills, and painful urination. The patient was diagnosed as likely having a urinary tract infection attributable to urethral obstruction. Blood and urine cultures were obtained, and the patient was discharged with oral levofloxacin antibiotic therapy. Two days later Escherichia coli was isolated from the blood and urine cultures, and the patient was called back to the hospital for admission. The patient was started on IV ampicillin sulbactam and later switched to intravenous cefipime and oral ciprofloxacin following antibiotic sensitivity reports. On the third day of hospitalization, the patient complained of jaw pain but, in general, was beginning to feel better. Because of the jaw pain, tests for cardiac markers were requested. The ECG showed only nonspecific isolated Q wave in lead III and the patient did not complain of any specific...

Sunburn 479

Given by mouth, these drugs are effective against a wide variety of infections such as urinary tract infection. Most (including sulfamethoxazole and sulfaphenazole) are quickly absorbed from the stomach and small intestine and should be taken at regular intervals. Others are long-acting (such as sulfadoxine, used to treat leprosy and malaria) and only need to be taken once a day.

Toilet Habits

Bathroom Habits Female

Fecal contamination of the vulva and perineum in young children is not always due to improper hygiene, but can result from fecal overflow around rectal blockage caused by constipation. This often unrecognized cause of fecal soiling is a precipitating or perpetuating factor in recurrent urinary tract infections (UTIs) in young girls. Because the anus and the urethra are closer in preme-narchal girls than in mature women, poor hygiene and toilet practices are often emphasized as a primary contributing factor. However, vulvar hygiene does not play a singular role. The most important risk factors for recurrent UTIs unrelated to physical abnormalities are a combination of

Concluding Remarks

Because lectin-mediated adhesion is a mechanism shared by many pathogens most investigators have focused their efforts to prevent bacterial infections on blocking the pathogen's lectins. The preferable target site is the mucosal surfaces where phagocytic cells are scarce and where most infections are initiated. A number of strategies have been suggested including enhancement of mucosal immunity by s-IgA anti-adhesin antibody induction, use of metabolic inhibitors of adhesin expression (e.g. sublethal concentration of antibiotics), and of dietary inhibitors, in particular receptor analogs (reviewed in Ofek and Doyle, 1994b Kahane and Ofek, 1996). In the latter strategy, the lectin or adhesin is inhibited by sugars for which the lectin is specific (Table 6). This was first demonstrated in the late 1970s, when it was shown that methyl a-mannoside can protect mice against urinary tract infection by type 1 fimbriated E. coli methyl a-glycoside which is not recognized by the bacteria, was...

Disease

Extraintestinal E. coli Two separate pathotypes of E. coli are generally recognized causes of extraintestinal human diseases (neonatal septicemia meningitis E. coli meningitis-associated E. coli, MAEC and the urinary tract and bloodstream E. coli uropathogenic E. coli, UPEC ). Some isolates, E. coli O18 K1 H7, are recognized as having the potential to cause both invasive neonatal diseases and urinary tract infections (UTI Johnson et al., 2001a Johnson et al., 2001b). UPEC are a heterogeneous group of clones (Donnenberg and Welch, 1996). Within the UPEC grouping are cystitis, pyelonephritis and urosepsis isolates. These strains are the principal causes of morbidity and mortality from either community or hospital-acquired E. coli infections. Approximately 60 of adult women will have a UTI in their lifetimes (Kunin, 1994). As much as 90 of all community-acquired UTIs and greater than 30 of the hospital-acquired UTIs are caused by E. coli (Haley et al., 1985). There have been reports of...

Yokenella Koserella

Al-Furayh, and K. Al-Qatary. 1992. Urinary tract infection due to Rahnella aquatilis in a renal transplant patient. J. Clin. Microbiol. 30 2948-2950. Dale, C., S. A. Young, D. T. Haydon, and S. C. Welburn. 2001b. The insect endosymbiont Sodalis glossinidius utilizes a type III secretion system for cell invasion. Proc. Natl. Acad. Sci. 98 1883-1888. De Baere, T., G. Wauters, A. Huylenbroeck, G. Claeys, R. Peleman, G. Verschraegen, D. Allemeersch, and M. Veneechoutte. 2001. Isolations of Leclercia adecarboxy-lata from a patient with a chronically inflamed gallbladder and from a patient with sepsis without focus. J. Clin. Microbiol. 39 1674-1675. De Champs, C., S. Le Seaux, J. J. Dubost, S. Biosgard, B. Sauvezie, and J. Sirot. 2000. Isolation of Pantoea agglo-merans in two cases of septic monoarthritis after plant thorn and wood sliver injuries. J. Clin. Microbiol. 38 460-461. Tristram, D. A., and B. A. Forbes. 1988. Kluyvera A case report of urinary...

The adult poisoner

Sparkes's trouble began on the evening of Wednesday, 10 February when he had a conversation with Young, who gave him a glass of water. During the night he was violently sick and had diarrhoea, which persisted for four days, accompanied by pains in his testicles. When he next played football the following Saturday he was still unwell and after a few minutes of play he had to leave the field. About six weeks after this incident Sparkes spent an evening with Young and drank some wine, after which he was again very ill. He went on Thursday, 8 April to see his doctor who diagnosed a urinary infection. Luckily Sparkes left Slough on Friday, 30 April and never saw Young again until his trial 15 months later. However, his troubles persisted throughout the summer of that year he was twice examined in hospital where he was treated for strain and muscular troubles, and it was not until the autumn of that year that he began to recover.

Thyroid Disease

Diabetes), other medical conditions (such as urinary tract infection, enlarged prostate, liver failure, multiple sclerosis, and sleep apnea), and medication (especially diuretics). Some cases are caused or exacerbated by excessive fluid intake after dinner, especially drinks containing alcohol or caffeine.

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