Replace Toxic Products in your home

Everyday Roots

This book includes home remedies, natural beauty recipes and Diy household product tutorials. Discover over 215 suprising natural home remedies using common ingredients like onion, lemons and apple cider vinegar. EveryDay Roots will help you to make healthy changes in your life. Learn how to treat coughs, headaches and other health conditions with common ingredients like honey and watermelon. When you buy the book you get a 328 page Pdf with a clickable table of contents. More here...

Everyday Roots Summary


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100% Natural Multi-purpose Cleaner

All natural enzymatic cleaner digests stains that are present around the home. This stain digester can be used in the kitchen area, on clothes, on the carper, on pet accessories, on furniture, and even in the bathroom. It removes stubborn stains naturally as compared to using chemicals. The multi enzyme formula works within minutes and breaks down organic soils, leaving the surface clean. Stains are made up of different types of molecules. To effectively remove those stains, a variety of enzymes are needed to break them down. For instance, enzyme protease breaks down proteins and therefore is the best for removal of blood, eggs, and other protein stains. Lipase, on the other hand, is best for the breakage of fats and grease whereas amylase is best used for the breakage of starch. The enzyme concentrate is all natural, non-toxic, versatile, super sturdy, and safe for colors for use on bright colors, pets, and even kids. In addition to that, the enzymatic cleaner can also be used by other living things with allergies and chemical sensitivities. The all natural enzymatic cleaner also remove stains that occurred years ago, as attested by different customers who have purchased it. More here...

100 Natural Multipurpose Cleaner Summary

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In the 1930s the class of drugs known as detergents, or as fatty acids and fatty alcohols, came into use with the introduction of sodium morrhuate and sodium tetradecyl sulfate. Detergent sclerosants work by a mechanism known as protein theft denaturation, in which an aggregation of detergent molecules forms a lipid bilayer in the form of a sheet, a cylinder, or a micelle, which then disrupts the cell surface membrane and may steal away essential proteins from the cell membrane surface. The solubility of detergents is inversely temperature dependent. Detergent molecules are much more soluble in cold solutions than in hot ones. This effect is easily seen in Glycerin is a polyalcohol that often is considered a chemical irritant sclerosant. It is classified here with the detergents because it is similar to the detergents in the way it causes cell surface protein denaturation. It is very popular in Europe, used as a 72 chromated solution marketed under the name Scleremo. It has not been...

More Industrious Microbes

Enzymatic proteases are well-known washing agents or biological detergents found in most laundry products. They help remove protein stains left by blood, sweat, or grass. Newer laundry additives include enzymes such as Lipolase that remove fat stains left by lipstick or butter and Celluzyme that softens fabrics made of cellulose fibrils. Released in 1988, Lipolase reportedly was the first industrial enzyme developed via genetic engineering.

Dermatitis contact 143

Keeping adequate hydration of the skin and avoiding irritants may be all that is required of children with mild cases. Irritants include wool clothing, strong detergents, and water. Irritants can be avoided by using a mild detergent (such as Ivory Snow flakes or Dreft), by avoiding wool, and by adding bath oil to bath water. Emollients such as white petrolatum should be applied immediately after bathing, and topical corticosteroids and tar preparations are useful. Oatmeal (Aveeno) baths are helpful, as is daily moisturizing with emollients such as Eucerin cream. Substances that are often implicated in contact dermatitis in children include metals (especially nickel), dyes and chemicals, cleaning products or detergents, latex, poison ivy, and insecticides. Latex is one of the most common irritating substances in children and may be found along the waist and legbands of underwear.

Structure And Properties Of Membrane Proteins

Although the lipids are very important for determining the barrier functions of the cell membrane, the membrane proteins confer most of the important functions of biological membranes. There are many different types of membrane proteins, reflecting their very different functions. Integral membrane proteins are those that cross the membrane with one or more transmembrane segments and are usually exposed to both sides of the membrane. They cannot be easily removed from the membrane unless detergents are added to disrupt the bilayer structure. Some integral membrane proteins are stably anchored to the membrane, usually by covalent attachment to a lipid such as a fatty acid, isoprenoid, phosphatidyl inositol, or a lipoprotein derivative. The membrane-spanning proteins include most of the functionally important transporters and signal receptors. Peripheral membrane proteins are defined operationally as those that are readily removed from association with the membrane by procedures that do...

Isolation Of Membranes

An alternative approach for separation of the proteins from the cytoplasmic and outer membranes in enteric bacteria takes advantage of the resistance of most outer membrane proteins to solubilization by nonionic detergents in the presence of divalent cations. This rapid method cannot be relied on for localization of all membrane proteins since it has been tested only on a limited set of proteins and depends on features that are not necessarily universally maintained. Detergents are amphipathic molecules that are able to associate with and disrupt membrane structure. They allow the lipids to form a spherical micel-lar structure and provide the membrane proteins with a suitable environment for their non-polar surfaces in molecular aggregates much smaller than the membrane. Many nonionic detergents allow membrane proteins to retain their structure and function.

Sanitizing agents and protein stability

To avoid the presence of trace amounts of sanitizing agents in the pharmaceutical industry as well as to avoid the presence of potential residues of cellular components in the biotechnology industry, the validation of cleaning between product lots becomes very important. In the manufacture of bio-pharmaceuticals by recombinant deoxyribonucleic acid (DNA) technology, potential residues can include proteins, nucleic acids, carbohydrates, endo-toxins, detergents, and the drug itself.

Why carbon monoxide is such a deadly killer

In contrast to carbon monoxide, which is responsible for many deaths as well as severe poisoning cases, the caustic and irritant chemicals in our homes such as bleach, drain and oven cleaners, kettle descalers, and strong detergents cleaners (for example, those in dishwasher powder) rarely cause death or serious injury. The most likely scenario is irritation of the skin or eyes by use of these caustic and irritant chemicals without protective measures such as the wearing of gloves. Children have occasionally drunk chemicals like bleach or caustic solutions, and can also suffer skin and eye damage after investigating the contents of the bottles found under the average household sink. This is not to say that serious and fatal poisonings don't occur as a result of the substances. Those intent on suicide may choose to end it all by drinking bleach or kettle descaler with fatal results.

Treatment of antifreeze poisoning

Because ethylene glycol is really poisonous only when it is metabolized, it is possible to reduce its toxic effects by stopping this metabolism. Alcohol is metabolized by the same enzyme, but binds to it in preference. So in an emergency the patient can be given a double or treble whisky. The alcohol will attach to the enzyme and the ethylene glycol will thus be excluded. This competitive inhibition of the enzyme stops the formation of the toxic products. Once in the Accident and Emergency department of the hospital, more alcohol can be given to the victim by infusing it into a vein. When it is used in this way, the alcohol is acting as an antidote. Another, specific antidote can also be used, but it is very expensive and is not always available.

Glue sniffing or solvent abuse

Other solvents that are found around the home can be hazardous if drunk and also if inhaled. The solvents found in glues, cleaning products, fire extinguishers, varnishes, paints, and spray cans are sometimes inhaled deliberately as a means of getting a pleasurable 'high'. This practice has lead to over 100 deaths in a year in the UK. Solvents commonly used for this are toluene, found in glues, and the halogen-containing solvents such as trichloroethane. Gases such as butane are also some times inhaled. The acute and long-term effects of these solvents depends on the particular solvent, for example trichloroethane will damage the heart if inhaled repeatedly. The halogenated solvents are also particularly hazardous after single exposures because they can sensitize the heart, with the result that a sudden fright, which causes a rush of adrenaline in the blood, can lead to arrythmias of the heart and sudden death from a heart attack, even in healthy young people. There are concerns that...

The application of the growth reaction to medium design

Stated in Section 5 from the experimental reaction flux data and, if the enthalpy change balances the observed heat flux, then the description of the growth reaction is correct. It should be remembered, however, that batch cultures are not in steady state 49 . Consequently, the metabolic flux and the heat flux that is a function of it must change to reflect alterations in the environmental conditions, including substrate availability and the accumulation of toxic products. Experimental evidence for this claim was seen for the CHO320 cells by the differing fluxes during the batch culture (see Fig. 5). Guan and Kemp 49 assayed all the major substrates and products at approximately 24-h int ervals and then constructed the necessary equations for the metabolic, catabolic and anabolic reactions. The data reflected the alterations in metabolism with the dynamically changing environment. In particular, the reaction equations showed the demand for substrates with time. As an illustration 49 ,...

Desoxy See under deoxy

Detergents Amphipathic, surface active, molecules with polar (water soluble) and non-polar (hydrophobic) domains. They bind strongly to hydrophobic molecules or molecular domains to confer water solubility. Examples include sodium dodecyl sulphate, fatty acid salts, the Triton family, octyl glucoside.

Global carbon cycle

Methylotrophic bacteria can also grow on some methylated sulfur compounds found in toxic wastes, such as paper mill effluents. Others can degrade aliphatic sulfonates and, therefore, may be important in degradation of detergents and related compounds in the environment. Research is under way to investigate the metabolism of halogenated methanes and one-carbon compounds containing sulfur, in order to be able to explore the bioremediation potential and to exploit the properties of these novel methylotrophs.

Protection from Ototoxins

Little is known about protection from ototoxicity. Anti-oxidants protect partially from noise or toxins in several animal models (Rybak, Whitworth, and Somani, 1999). In theory, prevention of reactive oxygen species, neutralization of toxic products, and blockage of the apop-tosis pathway might provide protection from oxidative stress, which is a common final pathway for ototoxicity. Toxic waste products can be neutralized with gluta-thione and derivatives (Rybak et al., 2000). Apoptosis can be blocked using capsase inhibitors. At this writing, all of these approaches are investigational and are not being used clinically. Most also require delivery systems that go directly into the inner ear, and are therefore impractical for clinical use. For cochleotoxicity, noise avoidance is likely helpful, but even here the story is complicated. Paradoxically, moderate amounts of noise may protect from extreme amounts of noise. Nevertheless, it seems prudent to avoid excessive noise exposure,...

From Inclusion Bodies of Escherichia coli Cells

Inclusion bodies produced in Escherichia coli are composed of densely packed denatured protein molecules in the form of particles (1,2). In addition to the recombinant protein of interest, inclusion bodies contain small amounts of host protein, ribo-somal components, and DNA RNA fragments (3). It is advisable to purify the inclusion bodies from the cells to a high-degree purity before carrying out solubilization and purification. This will reduce the number of purification steps after solubilization and refolding, minimize the interference of other contaminating proteins during refolding, and result in a therapeutic protein free from other cellular contaminants, such as lipids, carbohydrate, and endotoxin (4). Isolation of inclusion bodies from E. coli occurs by cell lysis with high-pressure disruption using a French press or sonication step followed by centrifugation (5). Further purification can be achieved by washing with detergents and a low concentration of salt and or urea...

Functions And Biological Activities Of Lipopolysaccharides

In E. coli and Salmonella, the phosphoryla-ted Hep-region of the core OS is crucial for outer membrane stability by facilitating the cross-linking of adjacent LPS molecules by divalent cations or polyamines and by its interaction with positively charged groups on proteins. The inability to synthesize or incorporate Hep, or the loss of phosphoryl derivatives alone (i.e. a waaP mutant), gives rise to significant compositional and structural changes in the outer membrane. In E. coli, these mutants are known as deep-rough and their perturbed outer membrane structure leads to pleiotropic phenotypes, most notably hypersensitivity to hydrophobic compounds, such as detergents, dyes, and some antibiotics. Salmonella waaP mutants are avirulent and in P. aeruginosa, waaP is an essential gene. For such bacteria, assembly and phosphorylation of the core OS Hep-region may therefore provide further avenues for therapeutic intervention.

Biotechnology Of Extremophiles

A major impetus driving research on extremophiles is the biotechnological potential associated with the microorganisms and their cellular products. In 1992, of the patents related to Archaea, about 60 were for methanogens, 20 for halophiles, and 20 ther-mophiles. Examples of extremozymes that are presently used commercially include alkaline proteases for detergents. This is a huge market, with 30 of the total worldwide enzyme production for detergents. In 1994, the total market for alkaline proteases in Japan alone was 15,000 million yen. DNA polymerases have been isolated from the hyperthermophiles Thermus aquaticus, Thermotoga maritima, Thermococcus litoralis, DNA amplification by PCR Diagnostics Dairy products Detergents Molecular biology Detergents Detergents

Hypertonic And Ionic Solutions

Strong solutions of hypertonic saline and other salt solutions are part of a class of solutions that often are referred to as osmotic sclerosants. These solutions have long been regarded as causing endothelial death by osmotic cellular dehydration. Although it is true that osmotic dehydration at the point of injection is sufficient to rupture red blood cells and to dehydrate some nearby endothelial cells, the evidence suggests that these sclerosants are effective even after dilution has reduced the osmotic gradient far too low to account for the effects seen. Thermodynamic and physical chemical calculations suggest that these and other strong ionic solutions probably work by causing conformational denaturation of cell membrane proteins in situ. Like the detergents, they can be diluted to the point where they have no further cellular toxicity.

Differential Diagnosis of Metabolic Acidoses

An interesting finding in this case was an elevation in total serum calcium, with decreased ionized calcium. Ethylene glycol and methanol intoxication typically cause hypocalcemia, and monitoring of this electrolyte is important to prevent cardiac arrhythmia. In health, approximately 40 of calcium is protein-bound, 10 is bound to organic and inorganic anions, and the remaining 45 is the physiologically active free calcium. In this case, the two alcohol groups of polyethylene glycol were metabolized to car-boxylic acids, thus producing diacid metabolites. The diacid metabolites of low-molecular-weight PEGs are known binders of calcium that have been used as phosphate substitutes in detergents. Binding of calcium by these metabolites in plasma decreased free calcium, which led to increased secretion of parathyroid hormone and mobilization of calcium from bone, and, thus, increased total serum calcium. As the physiologically active free calcium was decreased, monitoring of this fraction...

Approaches to overcome barriers to nasal absorption

Include bile salts, surfactants, fusidates, phospholipids, and cyclodextrins. Lysophosphatidylcholine, a lysophospholipid, has been reported to enhance the nasal absorption of biosynthetic hGH in the rat to achieve a relative bioavailability of 25.8 . In this study, a mucolytic agent, N-acetyl-L-cysteine, and a transmembrane fatty acid transporter, palmitoyl-DL-carnitine, were also found to promote the nasal absorption of hGH, with relative bioavail-abilities of 12.2 and 22.1 , respectively.103 A mucoadhesive and cationic polysaccharide, chitosan, has been reported to enhance the absorption of insulin across the nasal mucosa of rat and sheep. Although mucoadhesion may be partly responsible, it is also possible that the cationic nature of chitosan has a transient effect on the gating function of tight junctions.104 Alkylglycosides, a family of nonionic detergents, have also been shown to effectively enhance the nasal absorption of insulin in rats.105 The use of fusidates, bile salts,...

Sperm Whale Oils and Jojoba Waxes

The sperm whale is among the largest mammals in the world, capable of reaching 80 feet or more in length, with a weight of 40 tons. However, it was not so much the blubber surrounding the leviathan's body that whalers sought, but rather a fine waxy oil filling a cavernous organ, the spermaceti, inside the whale's prodigious head. The spermaceti, from which the species name derives, holds up to 500 gallons of the precious cream that whalers sold for use as lamp oil, candle wax, watch lubricants, and, more recently, additives for motor oils and transmission fluids, rust-proofing agents, detergents, lubricants for delicate high-altitude instruments, cosmetic bases, and more than 70 pharmaceutical compounds. Beginning in the mid-i800s, kerosene and other petroleum products steadily replaced sperm oil as affordable illuminants and greases, but other uses kept demand high for this exceptional whale substance.

How D-gln Form Peptide Bond With L-lysine In Peptidoglycan

By a wide range of natural and synthetic phospholipids and detergents. Initially it was suggested that phosphatidylglycerol or diphos-phatidylglycerol (cardiolipin) were specific lipid co-factors. However, enzymatic activity appears to be more dependent on lipid hydration rather than lipid viscosity or the actual chemical structure of the polar group of the activating lipid (Sanderman, 1976). In stationary-phase cultures, free undecaprenol was present in large excess, representing approximately 80 of the total peptidoglycan lipid. Investigation of the microenvironment in membranes of the fluorescent lipid intermediate suggests that the lipid intermediate is immobilized within hydrophobic environment close to the membrane surface. This observation is supported by the earlier finding that spinlabelled lipid intermediate could still form complexes with vancomycin and ristocetin (Johnston and Neuhaus, 1975). It was proposed that at least the terminal D-alanyl-D-alanine-dipeptide of the...

Cleanliness And Odorcontrol Products Soaps Body Washes and Bubble Bath

Yeast Soap Note

Soap making remained largely a household chore until the mid-19th century. At about this time, high-yield methods were developed for making soda ash or sodium carbonate out of common table salt, thereby improving the quality and yield of soap products, lowering the cost, and facilitating a move toward the commercial manufacturing of soap. These discoveries, along with the development of power to operate factories, made soapmaking one of America's fastest-growing industries by 1850 and changed soap from a luxury item to an everyday necessity. Investigation into the use of synthetic detergents began in the early 1900s and, with the end of World War II, synthetics starting replacing soaps for some cleaning chores, such as laundry and household cleaning (Fig. 1B). As surfactant chemistry became more and more sophisticated, these synthetic detergents began to replace soap in many of the bars and liquids used for personal cleansing. Synthetic detergents are synthesized or put together...

Ultrasound Monitoring During Sclerofoam Ablation Of Varicose Veins


Advent of foam sclerotherapy has added a new tool for the treatment of chronic venous insufficiency. Sclerosant agents provoke endothelial damage by several mechanisms.25 They change either the surface tension of the plasma membrane (detergents) or the intravascular pH and osmolarity. The final result is a chemical fibrosis of the treated

Molecular Studies Strain Variation

The main challenges to the application of PCR to Crypto-sporidium are extracting DNA from the sporozoites within the robust oocysts and avoiding the effect of any inhibitors that might be present in the initial sample. Furthermore, the selection of the appropriate polymerase for a particular biological sample type may be critical since polymerases can be differentially denatured, or inhibited by, for example, proteinases, phenols and detergents present in the sample matrix. Over-coming inhibitors has been achieved by the use of preliminary purification steps to remove sample matrix material. Purification methods include floating oocysts from faecal matter using two-phase systems (e.g. saturated salt solutions) or recovering oocysts from the sample matrix by immunomagnetic separation. Boiling the sample destroys inhibitors, while DNA extraction methods and kits remove inhibitory substances (Boom et al., 1990 Elwin et al., 2001 Xiao et al., 2001a).

Characteristics Of Bacillus Subtilis

Forespore Definition Microbiology

Bacillus species produce a range of enzymes and antibiotics in response to nutrient limitation. The enzymes include proteases, amylases, cellulases and lipases. Production is maximal when cells are in the stationary phase of the growth cycle. Production of these enzymes is presumably a survival strategy to scavenge macromolecular energy sources when nutrient levels are low. Many of these enzymes are widely used in the food, brewing, and biological washing powder industries. Enzymes with useful properties, such as thermostability, activity over a wide pH range, activity in detergents and oxidizing environments, have been identified in many Bacillus species. The role of B. subtilis in the enzyme industry is twofold (i) Many Bacillus species are refractory to genetic analysis and B. subtilis is therefore the organism of choice to study the regulation of enzyme production and (ii) heterologous genes encoding enzymes with desirable properties can be cloned into B. subtilis strains which...

Why antifreeze is poisonous

The ethylene glycol and methyl alcohol (see below), which is also sometimes found in antifreeze, are poisonous because they are converted into more toxic products. Once inside the body, the ethylene glycol in the antifreeze is changed by metabolism into first one, and then several other chemicals. This requires the same enzyme that metabolizes the alcohol we consume in alcoholic drinks (ethyl alcohol). The ethylene glycol is converted into oxalic acid which is poisonous, and other poisonous products are also produced. Oxalic acid is also found in rhubarb leaves, which is what makes them poisonous. The result of these metabolic conversions is that the acidity of the blood increases (the pH decreases) and normal metabolic processes are inhibited. The oxalic acid formed can crystallize in the brain and the kidneys, causing damage. The oxalic acid also reacts with calcium and removes it from the body. The reduction of calcium

Applications Of Biosensors

(1998) investigated a novel sensor which uses a human estrogen receptor and an SPR-detection system. Microbial sensors have been constructed which detect cyanide and detergents. Karube et al. (1995) reviewed developments in microbial sensors for environmental monitoring.

Cornucopia of GM Products

Genetic strains of cotton have been engineered for better fiber performance. Rapeseed plants have been genetically altered to provide improved raw materials for soaps and detergents. Flowering mustard plants are under investigation that produce cellulase, an enzymatic protein used in the production of alcohol. Interestingly, the enzyme remains inactive in the living plant (and thus is unlikely to harm it), but activates when artificially exposed to high temperatures after the plant is harvested. Tobacco plants have been engineered for lowered nitrosamine and nicotine content, the goal being to manufacture cigarettes that are less harmful and less addictive.

The Ups In Huntingtons Disease

In summary, the results of decreased cleavage of proteasome fluorogenic substrates on brain homogenates strongly supports an inhibition of the UPS in HD. However, apart of the above mentioned, this experimental approach has many limitations because 20S proteasome in a tissue homogenate can be in a latent form or in an activated form depending on whether detergents or hydrophobic peptides are present during the procedure (41,42) and depending on the content of each tissue in proteasome activators such as the 19S and PA28 complexes (43). For this reason, additional experiments will be required for a full elucidation on how the 20S catalytic activity is impaired in HD. This might be for instance by direct interaction of htt aggregates with the 20S proteasome particle. This possible mechanism can be tested now that a procedure for isolation of htt filaments from HD mice and patients brain has been described (11). In a similar way to what has been done before with purified paired helical...

Prion Protein The Friendly

Sestamibi Scan

The pathophysiology of prion disorders is both fascinating and perplexing. According to the prion hypothesis, PrPSc is the main culprit that catalyzes the conversion of host PrPC from a mainly a-helical structure to the pathogenic P-sheet rich PrPSc form. Unlike PrPC, PrPSc is insoluble in non-ionic detergents, resists limited digestion by proteinase-K (PK), and oligomerizes into amyloid (1-7, 10). Deposits of PrPSc in the brain parenchyma are believed to be the principal cause of neuronal death in these disorders (4, 5). However, prion disorders often occur in the absence of detectable PrPSc, and deposits of PrPSc have been identified in the absence of disease, raising legitimate doubts about whether PrPSc is identical with prion.

Food Contamination

Contrary to popular belief, application of chemical substances, such as pesticides or fertilizers, in food production is not as harmful as rumors and urban myths would seem to indicate. Pesticides eliminate pests that would otherwise be a frequent cause of poisoning of grains, vegetables, and fruit due to the toxic products of their metabolisms. Chemically synthesized fertilizers are more easily detectable in food than their natural substitutes, which facilitates their adoption for use on food products (Moghissi 1998).

Other examples

There may well be other examples of this phenomenon, where subclinical concentrations of an antibiotic could serve as selection for the maintenance (and propagation) of genetic elements and their resident resistance genes. There is also maintenance by constant selection pressure for other phenotypes, a type of linked selection (we have mentioned the role of mercury in this respect). How else does one explain the fact that streptomycin and chloramphenicol resistance can be still found on plasmids in hospitals, even though these antibiotics are no longer used Are there other positive selective functions carried by plas-mids Resistance to ultraviolet light or other physical or chemical toxins (e.g. detergents, disinfectants) would be a possibility. Is it also conceivable that plasmids improve the fitness of their hosts under normal conditions Evidence for this comes from the work of Lenski (personal communication, 1996).


Although ESI is generally tolerant of low levels of buffers, salts, and detergents, these substances can either suppress the formation of analyte ions or form adducts with the ana-lyte interfering with molecular mass determination. ESI ionizes the analytes out of a solution thus, it is readily interfaced with high-performance liquid chromatography (HPLC) to eliminate contaminated substances from the analytes prior to ionization (3). High sensitivity can also be achieved with ESI when flow rates are reduced to 100 nL min or less (3). Furthermore, multiple protonation of proteins and peptides make amide bonds more prone to fragmentation during collision-induced dissociation (CID), thereby promoting the generation of tandem mass spectrum for protein identification.

Antennal complex

Anionic detergents Detergents in which the hydrophilic function is fulfilled by an anionic grouping. Fatty acids are the best-known natural products in this class, but it is doubtful if they have a specific detergent function in any biological system. The important synthetic species are aliphatic sulphate esters, e.g. sodium dodecyl sulphate (SDS or SLS).

Hemophilia 213

Since 1985, the risk of being exposed to HIV through clotting factors has dropped to practically nil. one reason is that donated blood is now screened for HIV. Another reason is that clotting factors are heated and purified by detergents and biochemicals that kill HIV. The centers for disease


Itching That familiar tickling sensation on the skin is the most prominent symptom in many skin diseases and allergies. Skin that is too dry and scaly commonly causes itching as well, and many drug reactions result in itching (especially reactions to codeine and some antibiotics). Some types of rough clothing, soap, and detergents can trigger an itching response in some sensitive children.

Chunking Information

Chunking is an organizational method of sorting a large group of items into subgroups on the basis of a common characteristic. Suppose I gave you the following list of twelve grocery items (and you happened not to have pen and paper handy) spring water, sponges, apples, dishwashing liquid, coffee, tangerines, lemonade, laundry detergent, grapes, milk, limes, paper towels. It would be difficult to remember twelve different items over the twenty minutes you needed to drive to the supermarket. By chunking them into three subgroups (fruit, beverages, household cleaning supplies), you make the information much more manageable because you've essentially reduced twelve items to three, using each sub-category as a cue for its four members.

Barrier function

In comparison with the cytoplasmic membrane and other biological membranes, the outer membrane exhibits strikingly reduced permeability to a wide variety of lipophilic compounds, including bile salts and other detergents, lipophilic antibiotics, and dyes. Lipopolysaccharide is primarily responsible for the barrier properties of the membrane. Permeation of lipophilic compounds across membranes requires the initial intercalation of the compound into the hydrophobic interior of the lipid bilayer. Penetration into the outer membrane is hindered in the presence of LPS for two reasons. Lipid A fatty acids are saturated therefore, they are more highly ordered and of lower mobility than those of a conventional phospholipid


Vulvar hygiene practices also can contribute to symptoms. Thus, clinicians must identify any chemical, mechanical, and moisture irritant(s) to which the vulva is exposed. Chemical irritant exposures include laundry detergents, fabric softeners, body soaps and washes, perfumes, depilatory creams, various hygiene wipes and douches, lubricants spermicides with sexual activity, topical prescription and nonprescription medications, and activities such as swimming in a chlorinated pool or using a hot tub. Mechanical exposures include tight-fitting clothing, such as exercise clothing, swim suits, and thong-type undergarments. Also, daily sanitary pad wear can cause mechanical irritation. The clinician should assess other forms of mechanical irritation, which include scrubbing the vulva with a wash cloth, shaving to remove pubic hair, piercing the labia or the clitoris, exercises such as bicycling, and sexual practices including the use of vibrators.


Detergents and disinfectants Feedback inhibition Food preservatives Formaldehyde Heavy metals Hydrogen sulfide Wastes that are toxic to anaerobic digesters are numerous and diverse. Perhaps the three most commonly reviewed types of toxicity are ammonia, hydrogen sulfide, and heavy metals. Additional types of toxic wastes are listed in Table 17.1 and may be found in simple household detergents and complex anthropogenic organic compounds. Household detergents that contain the dispersing agent lauryl sulfate burst the cell walls of bacteria. Anthropogenic organic compounds include solvents and pesticides. These compounds are either highly chlorinated or contain cyanide (CN).


Response to the unwise applications of chemical insecticides and antibiotics in prior decades. Furthermore, various GMOs will increasingly be used to biomanufacture environmentally friendly alternatives to traditional industrial substances such as poorly degradable plastics and detergents. The new genetic technologies of cloning and other forms of reproductive assistance may even help to rescue (at least in zoos) a few of the thousands of species endangered by human activities.

The Oil Eaters

Within a few weeks, however, divers discovered that the most contaminated area in the ship's hold was thriving with sea life. Mother Nature had set out to repair herself. Naturally occurring bacteria in the water responded to the disaster and grew. They used the oil like food, changing the toxic petroleum into a harmless substance, a process that occurs only when other nutrients like nitrogen are present. Researchers learned from this discovery. Instead of washing away the oil from the shoreline with detergents that were harmful to the wildlife, they sprayed nitrogen onto the oil to encourage the growth of the oil-eating bacteria.

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Healthy Chemistry For Optimal Health

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