Major funding for this investigation has been provided by Research Grant R01-NS11862 from the National Institute of Neurological Disorders and Stroke. Additional support has been supplied by the MD-PhD Program (Daniel J. Debowy, Edward H. Hu) and Honors Program for medical students (Shari Reitzen) at New York University School of Medicine, and by fellowships to summer interns (Maria Chu and Jill Sakai) sponsored by the Sackler Institute of Graduate Biomedical Studies of New York University. We thank Dr. Daniel Gardner for many helpful comments and criticisms of earlier versions of this chapter.

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