H452y

Clozapine 102 Responders GAS

(over 6 wk) 58 Nonresponders 178 Normal controls (British)

Clozapine 73 Responders GAS

(at least 73 Nonresponders

Clozapine SCZ or ScAD BPRS

(wk 10) 21 Responders

49 Nonresponders

Frequency of Try452 allele higher among nonresponders (11%) vs responders (6%)

Higher frequency of Try452 allele among nonresponders (16%) vs responders (6%) but not statistically significant

Higher frequency of Try452 allele among nonresponders (16%) vs responders (6%) but not statistically significant

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