Brain asymmetry and interhemispheric communication Anatomical aspects and possible sex differences

In the human, MRI and postmortem studies have detected an inverse relationship between total callosal size and functional brain lateralization as determined by several behavioral parameters, including handedness (Witelson, 1995). When the sexes are separated, it has been observed that the callosal isthmus (the region between the posterior third and the posterior fifth) correlates negatively with visual behavioral laterality measures in males but not in females (Witelson and Goldsmith, 1991...

Corpus callosum and brain lateralization

Witelson was the first to suggest that hand preference, interacting with gender, might also affect CC morphology (Witelson, 1985, 1989 Witelson and Goldsmith, 1991 Witelson and Nowakowski, 1991). In her postmortem studies, nonconsistently right-handed men showed larger total CC areas than consistently right-handed men or women. This suggested a relationship between laterality and callosal size, at least in men. Subsequent in vivo imaging studies, however, revealed equivocal results. Whereas...

Anatomy and morphometry of the corpus callosum

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Mapping Structural Alterations of the Corpus Callosum During Brain Development and Degeneration

Thompson, Katherine l. narr, rebecca e. blanton, and Arthur w. toga abstract In this chapter we review current neuroimaging research on the structure of the corpus callosum. The corpus callosum is the main fiber tract connecting the two brain hemispheres, consisting of approximately 200-350 million fibers in humans. Given the corpus callosum's importance in communicating perceptual, cognitive, mnemonic, learned, and volitional information between the hemispheres, it has not surprisingly...

Corpus Callosum Morphology in Relation to Cerebral Asymmetries in the Postmortem Human

Francisco aboitiz, andres ide, and ricardo olivares abstract In this chapter we present data of fine callosal structure in postmortem humans revealing regional differences in fiber composition that indicate differences in interhemi-spheric transfer between primary secondary sensorimotor areas, on the one hand, and higher-order cortical regions, on the other. In addition, we review evidence from studies concerning a negative relation between interhemispheric communication and brain...

Aging and the corpus callosum

The corpus callosum has been reported to maintain its shape and size during the third and fourth decades of life with a gradual decline in size during later years (Pujol et al., 1992). Ratio measurements of the corpus callosum as a proportion of midline internal skull surface area have been used to study aging effects while correcting for variations in head size (Laissy et al., 1993). Significant decreases were found in total callosal area without associated reductions in total brain size in...