Contents
Preface vii
List of Contributors ix
Part 1: The Clinical Challenge
1. Clinical Vascular Growth Factor Therapy for Neovascularization in Patients with Coronary Artery Disease 1
Jens Kastrup
2. The Strengths and Weaknesses of VEGF Adenovirus-Driven Angiogenesis 23 Petra Korpisalo, Tuomas T. Rissanen and Seppo Yla-Herttuala
3. Angiogenesis and Arteriogenesis in Diabetes Mellitus: Signal Transduction Defects as the Molecular Basis of Vascular Cell Dysfunction 33 Vadim Tchaikovski and Johannes Waltenberger
4. Endothelial Activation and Neointimal Hyperplasia:
A Double-Edged Sword 75
R. Khurana and M. Simons
Part 2: Novel Mechanical and Molecular Concepts
5. Pampering and Priming the Heart 85 M.J. Post, R.N.M. Cornelussen and F.W. Prinzen
6. Coronary Venous Retroinfusion: A Novel Venue of Regional
Induction of Neovascularization 109
Peter Boekstegers and Christian Kupatt
7. Integrative Pro-angiogenic Activation: HIF-1a Karen A. Vincent and Ralph A. Kelly
8. The Maturation of Vessels - A Limitation to Forced Neovascularization?
A. Banfi, P. Fueglistaler and R. Gianni-Barrera
9. Vascular and Neuronal Development: Intersecting Parallelisms and Crossroads
Serena Zacchigna, Carmen Ruiz de Almodovar, Peggy Lafuste and Peter Carmeliet
10. Cathelicidin Antimicrobial Peptides Modulate Angiogenesis Rembert Koczulla and Robert Bals
Contents 123
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