Adenoviruses (AdVs) are double-stranded DNA-viruses that yield high, but transient, gene expression in the target tissues . Depending on the deletions in the viral genome, AdVs have transgene capacity from 8kbp (first generation E1
Address for correspondence and reprint requests: Seppo Yla-Herttuala MD, PhD, FESC, Department of Molecular Medicine, A.I. Virtanen Institute, University of Kuopio, P.O. Box 1627, FIN-70211 Kuopio, Finland, Phone: +358-17-162075, Fax: +358-17-163751, E-mail:[email protected]
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