Con A binding sites See Con A receptors

Con A receptors A common misuse of the term receptor. Con A binds to the mannose residues of many different glycoproteins and glycolipids, and the binding is therefore not to a specific site. It could be argued that the receptor is the Con A and cells have Con A ligands on their surfaces; certainly this would be less confusing.

conalbumin Ovotransferrin Non-haem iron-binding protein found in chicken plasma and egg white.

conantokins Class of small peptides (17-21 residues) from cone shells (Conus spp.) that inhibit NMDA class of glutamate receptors.

concanamycin A Folimycin Specific inhibitor of vacuolar H+-ATPase isolated from Streptomyces sp.; inhibits perforin-based cytotoxic activity, mostly due to accelerated degradation of perforin by an increase in the pH of lytic granules. Other concanamycins have been isolated with slightly different characteristics.

concanavalin A Con A A lectin isolated from the jack bean, Canavalia ensiformis. See Table L1 (Lectins).

concatamer Two or more identical linear molecular units covalently linked in tandem. Especially used of nucleic acid molecules and of units in artificial polymers.

conchae Three pairs of turbinate bones (nasal conchae) protrude into the centre of the nasal cavity. Each concha is a cartilaginous or slightly ossified scroll that serves to increase the surface area of the nasal cavity.

condensation 1. Process of compression or increase in density. Chromosome condensation is a consequence of increased supercoiling that causes the chromosome to become shorter and thicker, and thus visible in the light microscope. 2. A condensation reaction in chemistry is one in which two molecules combine to form a single larger molecule with the concomitant loss of a relatively small portion as water or similar small molecule. 3. The product of the process, for example water droplets that have formed on a cold surface exposed to water vapour.

condensing vacuole Vacuole formed from the cis face of the Golgi apparatus by the fusion of smaller vacuoles. Within the condensing vacuole the contents are concentrated and may become semicrystalline (zymogen granules or secretory vesicles).

conditional mutation A mutation that is only expressed under certain environmental conditions - for example, temperature-sensitive mutants.

conditioned medium Cell-culture medium that has already been partially used by cells. Although depleted of some components, it is enriched with cell-derived material, probably including small amounts of growth factors; such cell-conditioned medium will support the growth of cells at much lower density and, mixed with some fresh medium, is therefore useful in cloning.

0 0

Post a comment