Sueki et al. (23) used electron microscopy to study punch biopsies of normal skin from black and white men. The study revealed statistically significant structural differences between the mast cells of black versus white skin (Table 10); black skin had larger mast cell granules, increased parallel-linear striations, and increased tryptase localized to parallel-linear striation. Further research should focus on investigating pro-inflammatory mediators and involve a larger participant pool.
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