The intensity of keratosis follicularis can vary in association with hormonal status. One study involving eight women found that the disease presented most often at the beginning of puberty and continued for years without interruptions.
Invariably, the cutaneous manifestations worsened during menstruation. In three patients, treatment with estrogen-containing oral contraceptives led to a marked improvement of the skin condition. Thus, it appears that higher estrogen levels improve the symptoms of keratosis follicularis (31).
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.