A discussion of vulvar physiology in the reproductive years is incomplete without reference to the menstrual cycle. This chapter describes hormonal and endometrial cycling leading to menstruation, the physical properties and composition of menses fluid, and investigations of the effects of menses and blood on vulvar skin.

A portion of this review appeared in Farage M, Warren R, Wang-Weigand S. The vulva is relatively insensitive to menses-induced irritation. Cutaneous Ocular Toxicol 2005; 24(4):243-246. Reprinted with permission from Taylor & Francis Group.

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