The vulvar skin has distinctive morphology and functional characteristics, including increased permeability, higher degree of hydration, and a tendency for irritation from some chemicals. Various bioengineering methods of assessment demonstrate the vulvar skin's difference from other skin, such as forearm skin, in qualities such as capacitance, blood flow, and water loss, which helps explain some of its clinical properties. There have been numerous studies that show the vulva's unique response to various irritants and allergens. Some chemicals produce higher, others lower, degrees of irritation in vulva skin that differs from forearm skin. Future studies should consider the vulva's unique properties and responses, and use the appropriate methods of testing and assessment for this specialized skin.
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