An Important Finding on Routine Screening

Joan K. Riley

A 53-year-old female was in excellent health when a mass was found in her right breast on an annual screening mammogram. A breast needle biopsy was performed and demonstrated the presence of an estrogen-receptor-positive ductal carcinoma in situ and an estrogen-receptor-negative invasive carcinoma on multiple margins. The mass was grade 2 out of 3 and measured 1 cm in diameter. The patient underwent a lumpectomy, and at this time the lymph nodes were negative. One month later the margin was positive on one side, and thus a right total mastectomy was performed. The patient was placed on tamoxifen (antiestrogen) and continued taking the drug for 5 years until a CT scan showed liver metastases. Subsequently the patient received chemotherapy with Taxotere (docetaxel; a mitotic inhibitor). It was later determined by immunohistochemistry (IHC) that her cancer overexpressed HER2/neu, and the patient began taking Herceptin (trastu-zumab). Two years later, a CT scan revealed progression of the disease. She was started on carboplatin (alkylating agent-platinum compound), Taxotere, and Herceptin. CA 15-3 was measured and was 24 U/mL (0-30 U/mL). One month later her CA 15-3 was 40 U/mL and 2 months later, it was 64 U/mL. A CT scan showed an increase in the size of the liver mass. Seven months later she presented for selective internal hepatic radiation therapy. Her CA 15-3 was 189 U/mL at this time. She continues to undergo chemotherapy.

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Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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