Tuning of inflammatory cytokines and tolllike receptors by TIR8SIGIRR a member of the IL1 receptor family with unique structure and regulation

Cecilia Garlanda1, Michela Mosca2, Alessia Cotena1, Virginia Maina1, Federica Moalli1, Federica Riva3 and Alberto Mantovani1,4

11stituto Clinico Humanitas, via Manzoni 56, 20089 Rozzano, Italy; 2Department of Pharmacological Sciences and Experimental Medicine, University of Camerino, via Scalzino 3, 62032 Camerino, Italy; 3Department of Animal Pathology, Faculty of Veterinary Medicine, University of Milan, via Celoria 10, 20133 Milan, Italy; 4Centro di Eccellenza per l'Innovazione Diagnostica e Terapeutica (IDET) Institute of General Pathology, Faculty of Medicine, University of Milan, Via Mangiagalli 31, 20133 Milan, Italy

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