Mutations in Y chromosome genes that cause infertility

Although a handful of individual genes have been mapped to the AZF regions on Yq, very few reports define precise mutations within a gene that are associated with male infertility. The best example is a de novo point mutation described in an azoospermic male that included four base pairs in the Yq gene USPY in the AZFa region (Sun et al., 1999). Another patient was found to have a deletion in the DEAD box Y (DBY) gene in the AZFa region, but the effect of the deletion on gene function was not fully analyzed (Foresta et al., 2000).

Pregnancy Guide

Pregnancy Guide

A Beginner's Guide to Healthy Pregnancy. If you suspect, or know, that you are pregnant, we ho pe you have already visited your doctor. Presuming that you have confirmed your suspicions and that this is your first child, or that you wish to take better care of yourself d uring pregnancy than you did during your other pregnancies; you have come to the right place.

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