In the U.S., microcrystalline cellulose has GRAS status and has been used safely in foods for over 30 years. In the European Union, in accordance with the EP/Council Directive
95/2/EC on Food Additives Other Than Colors and Sweeteners, microcrystalline cellulose
(E460i) is listed in Appendix I and Appendix II (for use in cream) at quantum satis (QS).
Sodium CMC, calcium alginate, and guar gum are also listed in Appendix I of this directive and are approved for use under numbers E466, E404, and E412, respectively.
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