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*Curcuminoids have been isolated from the plant indicated in bold. Source Modified from include antiseptic, analgesic, anti-inflammatory, antioxidant, antimalarial, insect-repellant, and other activities associated to turmeric.4'20-27 (Figure 3). Perhaps one of the most often prescribed uses is for wound-healing.28 This activity is well known to people from the Indian subcontinent. Modern research has provided considerable evidence, and the mechanism by which turmeric curcumin could accelerate...

Contributors

Anderson Cancer Center 1515 Holcombe Boulevard BOX 143 Houston, TX 77030, USA aggarwal mdanderson.org Associate Professor Department of Dermatology, Emory University School of Medicine Winship Cancer Institute 1639 Pierce Drive WMB 5309 Atlanta, GA 30322, USA jarbise emory.edu Deputy Director and Head Bio-Materials Laboratory CLRI, Chennai-600020, India marybabu hotmail.com Department of Dermatology Emory University School of Medicine Winship Cancer Institute 1639...

Introduction

The questions of whether medicines discovered today are safer, more efficacious, and more affordable than generic medicines (whose patents have expired) or medicines that are centuries old could be answered no for most of the modern medicines. If so, then it is logical to revisit and revive these age-old medicines for the welfare of mankind. Curcumin is one such medicine. Its history goes back over 5000 years, to the heyday of Ayurveda (which means the science of long life). Turmeric derived...

Composition Of Turmeric

Turmeric contains a wide variety of phytochemicals, including curcumin, demethoxycurcumin, bisdemethoxycurcumin, zingiberene, curcumenol, curcu-mol, eugenol, tetrahydrocurcumin, triethylcurcumin, turmerin, turmerones, and turmeronols.1 Curcumin, demethoxycurcumin, and bisdemethoxycurcumin have also been isolated from Curcuma mangga,2 Curcuma zedoaria,3 Costus speciosus,4 Curcuma xanthorrhiza,4 Curcuma aromatica,5 Curcuma phaeocaulis,5 Etlingera elatior,6 and Zingiber cassumunar1 (Figure 1 see...

Molecular Targets Of Turmericcurcumin

Most molecular targets established in modern biology were discovered within the last three decades. The effect of curcumin on most of these targets has Figure 3. Traditional uses of curcmin. (See also Plate 2 in the Color Plate Section.) Figure 3. Traditional uses of curcmin. (See also Plate 2 in the Color Plate Section.) been examined10'12'45'50-201 (Figure 4). The results have revealed that curcumin can modulate several different transcription factors,50-96'113'114 cytokines,45'97-112 growth...

Crossroads Between Innate And Adaptive Immunity

Katsikis, Bali Pulendran and Stephen P. Schoenberger Volume 591 SOMATIC CELL NUCLEAR TRANSFER Edited by Peter Sutovsky REGULATORY MECHANISMS OF STRIATED MUSCLE CONTRACTION Edited by Setsuro Ebashi and Iwao Ohtsuki MICROARRAY TECHNOLOGY AND CANCER GENE PROFILING Edited by Simone Mocellin MOLECULAR ASPECTS OF THE STRESS RESPONSE Edited by Peter Csermely and Laszlo Vigh