Sexually Transmitted Diseases

All of the fluoroquinolones are effective in single-dose treatment of uncomplicated urethral, anal, and oropharyngeal gonorrhoea [51], although such regimes are ineffective for chlamydial disease. Ofloxacin for 7 days is reliably effective in chlamydial urethritis in men, although possibly less so in women, but there are little data on genital Mycoplasma infection. Preliminary data on trovafloxacin suggest high efficacy at low single doses in gonorrhoea [52] and, after multiple dosing, for chlamydial sexually transmitted diseases (STDs). However, fluoroqui-nolones are not indicated in syphilis, and results in bacterial vaginosis suggest only a secondary role.

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