Abstract

General surgery is associated with a significant risk of venous thromboembolism (VTE). The high prevalence and frequently silent onset of this condition underscore the importance of risk assessment and appropriate prophylactic measures. Individual risk assessment is critical for the selection of appropriate prophylactic methods for general surgical patients. Intermittent pneumatic compression and graduated compression stockings have been shown to reduce the risk for postoperative development of VTE in moderate-risk surgical patients. In very high-risk surgical patients, such as those with malignant disease, pharmacologic prophylaxis given for up to four weeks is necessary. Unfractionated heparin and low-molecular-weight heparins are safe and effective for VTE prophylaxis in this patient population. However, recent data from prospective registries show that most patients who develop postoperative symptomatic VTE had received some form of prophylaxis, which was obviously ineffective.1 Therefore, more effective methods are necessary for very high-risk patients. A novel selective factor Xa inhibitor, fondaparinux, also has been shown to be safe and effective for VTE prophylaxis in patients who have undergone abdominal surgery, especially in patients with cancer. These results suggest that fondaparinux may further improve VTE prevention in the general surgical population. No method of VTE prophylaxis is appropriate for every patient; therefore, the benefits and risks of each method of VTE prophylaxis should be weighed for the individual patient so that the optimal prophylactic regimen can be initiated.

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

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