Thresholding and multiple comparisons

As discussed above, the massively univariate approach requires fitting a model at each of many voxels throughout the brain (often 100,000 or more), and constructing maps of the activation statistics and reliability over the brain (statistical parametric maps, or SPMs). In a typical behavioral experiment, test statistics whose p-values are below 0.05 are considered sufficient evidence to reject the null hypothesis, with an acceptable false positive rate (alpha) of 0.05. However, in a...

The Conceptualization Of Psychophysiology

The body is the medium of experience and the instrument of action. Through its actions we shape and organize our experiences and distinguish our perceptions of the outside world from sensations that arise within the body itself. (Miller, 1978, p. 14) Anatomy, physiology, and psychophysiology are all branches of science organized around bodily systems with the collective aim of elucidating the structure and function of the parts of, and interrelated systems in, the human body in transactions...

Four Categories Of Psychophysiological Relationships

Relations between elements in the psychological and physiological domains should not be assumed to hold across situations or individuals. Indeed, elements in the psychological domain are delimited in the subtractive method in part by holding constant other processes that might differentiate the comparison tasks. Such a procedure is no unique to psychophysiology or to the subtractive method, as most psychological and medical tests can involve constructing specific assessment contexts in order to...

Historical Developments

Psychophysiology is still quite young as a scientific field. Studies dating back to the turn of the prior century can be found involving the manipulation of a psychological factor and the measurement of one or more physiological responses (e.g., Berger, 1929 Darrow, 1929 Eng, 1925 Jacobson, 1930 Mosso, 1896 Peterson & Jung, 1907 Sechenov, 1878 Tarchanoff, 1890 Wenger, 1941 Wilder, 1931 see also, Woodworth & Schlosberg, 1954), and such studies would now be considered as falling squarely...