Contents

Introduction 3 Part I The Industrial Origins of Prontosil

1 Beginnings 15

2 A System of Invention 40

3 Prontosil 51

Part II The Making of the First Miracle Drugs

4 Into the Maelstrom 71

5 Accommodation and Survival 92

6 Pathways of Recognition 122

7 M&B 693 158

8 Acclaim and Expansion 184

Part III Practice and Theory

9 At War 207

10 Trial by Fire 222

11 A Mechanism Revealed 251

12 The Sulfa Drugs and Twentieth-Century Medicine 269

Notes 293 Index 349

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The First Miracle Drugs

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